Reaction Details  Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM50217078
Substrate
n/a
Meas. Tech.
ChEMBL_440457 (CHEMBL890772)
Ki
270±n/a nM
Citation
 Minutolo, F; Cascio, MG; Carboni, I; Bisogno, T; Prota, G; Bertini, S; Digiacomo, M; Bifulco, M; Di Marzo, V; Macchia, M Metabolically labile cannabinoid esters: a 'soft drug' approach for the development of cannabinoid-based therapeutic drugs. Bioorg Med Chem Lett 17:4878-81 (2007) [PubMed]  Article
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM50217078
Synonyms:
2-hydroxy-6-methoxy-3',5'-dimethyl-biphenyl-4-carboxylic acid pentyl ester | CHEMBL436801
Type:
Small organic molecule
Emp. Form.:
C21H26O4
Mol. Mass.:
342.4287
SMILES:
CCCCCOC(=O)c1cc(O)c(c(OC)c1)-c1cc(C)cc(C)c1
Structure:
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