Reaction Details  Report a problem with these data
Target
Mu-type opioid receptor
Ligand
BDBM50269312
Substrate
n/a
Meas. Tech.
ChEMBL_525304 (CHEMBL968093)
Ki
>10000±n/a nM
Citation
 Tidgewell, K; Harding, WW; Lozama, A; Cobb, H; Shah, K; Kannan, P; Dersch, CM; Parrish, D; Deschamps, JR; Rothman, RB; Prisinzano, TE Synthesis of salvinorin A analogues as opioid receptor probes. J Nat Prod 69:914-8 (2006) [PubMed]  Article
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44789.51
Organism:
Homo sapiens (Human)
Description:
P35372
Residue:
400
Sequence:
MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM50269312
Synonyms:
(2S,4aS,6aR,7R,9S,10aS,10bR)-9-(Benzenesulfonyloxy)-2-(3-furanyl)dodecahydro-6a,10b-dimethyl-4,10-dioxo-2H-naphtho[2,1-c]pyran-7-carboxylic Acid Methyl Ester | CHEMBL526700
Type:
Small organic molecule
Emp. Form.:
C27H30O9S
Mol. Mass.:
530.587
SMILES:
COC(=O)[C@@H]1C[C@H](OS(=O)(=O)c2ccccc2)C(=O)[C@H]2[C@@]1(C)CC[C@H]1C(=O)O[C@@H](C[C@]21C)c1ccoc1 |r|
Structure:
Search PDB for entries with ligand similarity: