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Target
Adenosylhomocysteinase
Ligand
BDBM50081472
Substrate
n/a
Meas. Tech.
ChEMBL_554798 (CHEMBL953951)
Ki
8800±n/a nM
Citation
 Kojima, H; Kozaki, A; Iwata, M; Ando, T; Kitade, Y Synthesis of 3',4'-epoxynoraristeromycin analogs for molecular labeling probe of S-adenosyl-l-homocysteine hydrolase. Bioorg Med Chem 16:6575-9 (2008) [PubMed]  Article
Target
Name:
Adenosylhomocysteinase
Synonyms:
AHCY | Adenosylhomocysteinase | SAHH | SAHH_HUMAN
Type:
PROTEIN
Mol. Mass.:
47714.06
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1507791
Residue:
432
Sequence:
MSDKLPYKVADIGLAAWGRKALDIAENEMPGLMRMRERYSASKPLKGARIAGCLHMTVETAVLIETLVTLGAEVQWSSCNIFSTQDHAAAAIAKAGIPVYAWKGETDEEYLWCIEQTLYFKDGPLNMILDDGGDLTNLIHTKYPQLLPGIRGISEETTTGVHNLYKMMANGILKVPAINVNDSVTKSKFDNLYGCRESLIDGIKRATDVMIAGKVAVVAGYGDVGKGCAQALRGFGARVIITEIDPINALQAAMEGYEVTTMDEACQEGNIFVTTTGCIDIILGRHFEQMKDDAIVCNIGHFDVEIDVKWLNENAVEKVNIKPQVDRYRLKNGRRIILLAEGRLVNLGCAMGHPSFVMSNSFTNQVMAQIELWTHPDKYPVGVHFLPKKLDEAVAEAHLGKLNVKLTKLTEKQAQYLGMSCDGPFKPDHYRY
  
Inhibitor
Name:
BDBM50081472
Synonyms:
(2S,3S)-4-(6-Amino-purin-9-yl)-2,3-dihydroxy-butyraldehyde | 9-[(2'S,3'S)-3'-formyl-2',3'-dihydroxypropyl]adenine | CHEMBL94110
Type:
Small organic molecule
Emp. Form.:
C9H11N5O3
Mol. Mass.:
237.2153
SMILES:
Nc1ncnc2n(C[C@H](O)[C@H](O)C=O)cnc12 |r|
Structure:
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