Reaction Details  Report a problem with these data
Target
Type-1 angiotensin II receptor
Ligand
BDBM50251488
Substrate
n/a
Meas. Tech.
ChEMBL_488661 (CHEMBL988351)
Ki
3±n/a nM
Citation
 Wallinder, C; Botros, M; Rosenström, U; Guimond, MO; Beaudry, H; Nyberg, F; Gallo-Payet, N; Hallberg, A; Alterman, M Selective angiotensin II AT2 receptor agonists: Benzamide structure-activity relationships. Bioorg Med Chem 16:6841-9 (2008) [PubMed]  Article
Target
Name:
Type-1 angiotensin II receptor
Synonyms:
AGTR1 | AGTR1_PIG
Type:
PROTEIN
Mol. Mass.:
40925.99
Organism:
Sus scrofa
Description:
ChEMBL_488661
Residue:
359
Sequence:
MILNSSTEDSIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPTIIHRNVFFIENTNITVCAFHYESQNSTLPVGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGIIHDCKIADIVDTAMPITICLAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSSLSTKMSTLSYRPSENGSSSTKKSAPCTEVE
  
Inhibitor
Name:
BDBM50251488
Synonyms:
CHEMBL521093 | N-Butoxycarbonyl-3-[4-(N,N-diethylcarbamoyl)phenyl]-5-isobutylthiophene-2-sulfonamide
Type:
Small organic molecule
Emp. Form.:
C24H34N2O5S2
Mol. Mass.:
494.667
SMILES:
CCCCOC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c1ccc(cc1)C(=O)N(CC)CC
Structure:
Search PDB for entries with ligand similarity: