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Target
Casein kinase I isoform delta
Ligand
BDBM50240382
Substrate
n/a
Meas. Tech.
ChEMBL_535967 (CHEMBL987141)
IC50
>40000±n/a nM
Citation
 Cozza, G; Gianoncelli, A; Montopoli, M; Caparrotta, L; Venerando, A; Meggio, F; Pinna, LA; Zagotto, G; Moro, S Identification of novel protein kinase CK1 delta (CK1delta) inhibitors through structure-based virtual screening. Bioorg Med Chem Lett 18:5672-5 (2008) [PubMed]  Article
Target
Name:
Casein kinase I isoform delta
Synonyms:
CKI-delta | CKId | CSNK1D | Casein kinase 1 delta (CK1δ) | Casein kinase I delta | Casein kinase I isoform alpha/delta | Casein kinase I isoform delta (CK1D) | HCKID | KC1D_HUMAN | casein kinases 1 delta (CK1 delta)
Type:
Enzyme
Mol. Mass.:
47356.76
Organism:
Homo sapiens (Human)
Description:
P48730
Residue:
415
Sequence:
MELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQGGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGASRAADDAERERRDREERLRHSRNPATRGLPSTASGRLRGTQEVAPPTPLTPTSHTANTSPRPVSGMERERKVSMRLHRGAPVNISSSDLTGRQDTSRMSTSQIPGRVASSGLQSVVHR
  
Inhibitor
Name:
BDBM50240382
Synonyms:
1,4-Dihydroxyanthrachinon | 1,4-dihydroxy-9,10-anthraquinone | 1,4-dihydroxyanthra-9,10-quinone | 1,4-dihydroxyanthracene-9,10-dione | 1,4-dihydroxyanthraquinone | CHEMBL17594 | Chinizarin | quinizarin | quinizarine
Type:
Small organic molecule
Emp. Form.:
C14H8O4
Mol. Mass.:
240.2109
SMILES:
Oc1ccc(O)c2C(=O)c3ccccc3C(=O)c12
Structure:
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