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Target
Group 10 secretory phospholipase A2
Ligand
BDBM50274388
Substrate
n/a
Meas. Tech.
ChEMBL_537139 (CHEMBL989799)
IC50
>1600±n/a nM
Citation
 Oslund, RC; Cermak, N; Verlinde, CL; Gelb, MH Simplified YM-26734 inhibitors of secreted phospholipase A2 group IIA. Bioorg Med Chem Lett 18:5415-9 (2008) [PubMed]  Article
Target
Name:
Group 10 secretory phospholipase A2
Synonyms:
Group X secretory phospholipase A2 | PA2GX_MOUSE | Pla2g10
Type:
PROTEIN
Mol. Mass.:
17005.09
Organism:
Mus musculus
Description:
ChEMBL_537139
Residue:
151
Sequence:
MLLLLLLLLLGPGPGFSEATRRSHVYKRGLLELAGTLDCVGPRSPMAYMNYGCYCGLGGHGEPRDAIDWCCYHHDCCYSRAQDAGCSPKLDRYPWKCMDHHILCGPAENKCQELLCRCDEELAYCLAGTEYHLKYLFFPSILCEKDSPKCN
  
Inhibitor
Name:
BDBM50274388
Synonyms:
2-Phenyl-1-(2,4,6-trihydroxy-3-methyl-5-phenylacetyl-phenyl)-ethanone | CHEMBL520514
Type:
Small organic molecule
Emp. Form.:
C23H20O5
Mol. Mass.:
376.4019
SMILES:
Cc1c(O)c(C(=O)Cc2ccccc2)c(O)c(C(=O)Cc2ccccc2)c1O
Structure:
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