Reaction Details  Report a problem with these data
Target
Phospholipase A2, membrane associated
Ligand
BDBM50274337
Substrate
n/a
Meas. Tech.
ChEMBL_537136 (CHEMBL989796)
IC50
60±n/a nM
Citation
 Oslund, RC; Cermak, N; Verlinde, CL; Gelb, MH Simplified YM-26734 inhibitors of secreted phospholipase A2 group IIA. Bioorg Med Chem Lett 18:5415-9 (2008) [PubMed]  Article
Target
Name:
Phospholipase A2, membrane associated
Synonyms:
PA2GA_MOUSE | Pla2g2a
Type:
PROTEIN
Mol. Mass.:
16162.44
Organism:
Mus musculus
Description:
ChEMBL_352635
Residue:
146
Sequence:
MKVLLLLAASIMAFGSIQVQGNIAQFGEMIRLKTGKRAELSYAFYGCHCGLGGKGSPKDATDRCCVTHDCCYKSLEKSGCGTKLLKYKYSHQGGQITCSANQNSCQKRLCQCDKAAAECFARNKKTYSLKYQFYPNMFCKGKKPKC
  
Inhibitor
Name:
BDBM50274337
Synonyms:
1-(3-Dodecanoyl-2,4,6-trihydroxy-5-methyl-phenyl)-dodecan-1-one | CHEMBL485601
Type:
Small organic molecule
Emp. Form.:
C31H52O5
Mol. Mass.:
504.7416
SMILES:
CCCCCCCCCCCC(=O)c1c(O)c(C)c(O)c(C(=O)CCCCCCCCCCC)c1O
Structure:
Search PDB for entries with ligand similarity: