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Target
Amine oxidase [flavin-containing] A
Ligand
BDBM50246265
Substrate
n/a
Meas. Tech.
ChEMBL_557971 (CHEMBL965566)
IC50
3.78±n/a nM
Citation
 Santana, L; González-Díaz, H; Quezada, E; Uriarte, E; Yáñez, M; Viña, D; Orallo, F Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. J Med Chem 51:6740-51 (2008) [PubMed]  Article
Target
Name:
Amine oxidase [flavin-containing] A
Synonyms:
AOFA_HUMAN | Amine oxidase (flavin-containing) A | MAO-A | MAOA | Monoamine oxidase | Monoamine oxidase type A | Monoamine oxidase type A (MAO A) | Monoamine oxidase type A (MAO A) | Monoamine oxidase type A (MAOA)
Type:
Protein
Mol. Mass.:
59689.53
Organism:
Homo sapiens (Human)
Description:
P21397
Residue:
527
Sequence:
MENQEKASIAGHMFDVVVIGGGISGLSAAKLLTEYGVSVLVLEARDRVGGRTYTIRNEHVDYVDVGGAYVGPTQNRILRLSKELGIETYKVNVSERLVQYVKGKTYPFRGAFPPVWNPIAYLDYNNLWRTIDNMGKEIPTDAPWEAQHADKWDKMTMKELIDKICWTKTARRFAYLFVNINVTSEPHEVSALWFLWYVKQCGGTTRIFSVTNGGQERKFVGGSGQVSERIMDLLGDQVKLNHPVTHVDQSSDNIIIETLNHEHYECKYVINAIPPTLTAKIHFRPELPAERNQLIQRLPMGAVIKCMMYYKEAFWKKKDYCGCMIIEDEDAPISITLDDTKPDGSLPAIMGFILARKADRLAKLHKEIRKKKICELYAKVLGSQEALHPVHYEEKNWCEEQYSGGCYTAYFPPGIMTQYGRVIRQPVGRIFFAGTETATKWSGYMEGAVEAGERAAREVLNGLGKVTEKDIWVQEPESKDVPAVEITHTFWERNLPSVSGLLKIIGFSTSVTALGFVLYKYKLLPRS
  
Inhibitor
Name:
BDBM50246265
Synonyms:
7-Acetonyloxy-3,4-cyclohexene-8-methylcoumarin | CHEMBL488073
Type:
Small organic molecule
Emp. Form.:
C17H18O4
Mol. Mass.:
286.3224
SMILES:
CC(=O)COc1ccc2c3CCCCc3c(=O)oc2c1C
Structure:
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