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Target
Galanin receptor type 1
Ligand
BDBM50256705
Substrate
n/a
Meas. Tech.
ChEMBL_515047 (CHEMBL1034789)
IC50
11.1±n/a nM
Citation
 Terui, Y; Chu, YW; Li, JY; Ando, T; Fukunaga, T; Aoki, T; Toda, Y New cyclic tetrapeptides from Nonomuraea sp. TA-0426 that inhibit glycine transporter type 1 (GlyT1). Bioorg Med Chem Lett 18:6321-3 (2008) [PubMed]  Article
Target
Name:
Galanin receptor type 1
Synonyms:
GALR1_RAT | Galanin R1 | Galanin receptor type 1 | Galnr | Galnr1 | Galr1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
38883.91
Organism:
RAT
Description:
Galanin R1 GALR1 RAT::Q62805
Residue:
346
Sequence:
MELAPVNLSEGNGSDPEPPAEPRPLFGIGVENFITLVVFGLIFAMGVLGNSLVITVLARSKPGKPRSTTNLFILNLSIADLAYLLFCIPFQATVYALPTWVLGAFICKFIHYFFTVSMLVSIFTLAAMSVDRYVAIVHSRRSSSLRVSRNALLGVGFIWALSIAMASPVAYYQRLFHRDSNQTFCWEHWPNQLHKKAYVVCTFVFGYLLPLLLICFCYAKVLNHLHKKLKNMSKKSEASKKKTAQTVLVVVVVFGISWLPHHVIHLWAEFGAFPLTPASFFFRITAHCLAYSNSSVNPIIYAFLSENFRKAYKQVFKCRVCNESPHGDAKEKNRIDTPPSTNCTHV
  
Inhibitor
Name:
BDBM50256705
Synonyms:
(3S,6S,9S,12S)-3-benzyl-6-((2S,3R)-3-hydroxybutan-2-yl)-9,12-diisopropyl-1,4,7,10-tetraazacyclododecane-2,5,8,11-tetraone | CHEMBL474038
Type:
Small organic molecule
Emp. Form.:
C25H38N4O5
Mol. Mass.:
474.593
SMILES:
CC(C)[C@@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)[C@@H](NC1=O)C(C)C)[C@H](C)[C@@H](C)O |r|
Structure:
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