Reaction Details  Report a problem with these data
Target
Galanin receptor type 2
Ligand
BDBM50256745
Substrate
n/a
Meas. Tech.
ChEMBL_515048 (CHEMBL1034790)
IC50
21.1±n/a nM
Citation
 Terui, Y; Chu, YW; Li, JY; Ando, T; Fukunaga, T; Aoki, T; Toda, Y New cyclic tetrapeptides from Nonomuraea sp. TA-0426 that inhibit glycine transporter type 1 (GlyT1). Bioorg Med Chem Lett 18:6321-3 (2008) [PubMed]  Article
Target
Name:
Galanin receptor type 2
Synonyms:
GALR2_RAT | Galanin R2 | Galanin receptor 2 | Galanin receptor type 2 | Galnr2 | Galr2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
40697.04
Organism:
RAT
Description:
Galanin R2 GALR2 RAT::O08726
Residue:
372
Sequence:
MNGSGSQGAENTSQEGGSGGWQPEAVLVPLFFALIFLVGTVGNALVLAVLLRGGQAVSTTNLFILNLGVADLCFILCCVPFQATIYTLDDWVFGSLLCKAVHFLIFLTMHASSFTLAAVSLDRYLAIRYPLHSRELRTPRNALAAIGLIWGLALLFSGPYLSYYRQSQLANLTVCHPAWSAPRRRAMDLCTFVFSYLLPVLVLSLTYARTLRYLWRTVDPVTAGSGSQRAKRKVTRMIIIVAVLFCLCWMPHHALILCVWFGRFPLTRATYALRILSHLVSYANSCVNPIVYALVSKHFRKGFRKICAGLLRPAPRRASGRVSILAPGNHSGSMLEQESTDLTQVSEAAGPLVPPPALPNCTASSRTLDPAC
  
Inhibitor
Name:
BDBM50256745
Synonyms:
(2S)-2-amino-3-((2-(benzyloxy)phenyl)(3-fluorophenyl)methoxy)propanoic acid | CHEMBL475562
Type:
Small organic molecule
Emp. Form.:
C23H22FNO4
Mol. Mass.:
395.4235
SMILES:
N[C@@H](COC(c1cccc(F)c1)c1ccccc1OCc1ccccc1)C(O)=O |r|
Structure:
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