Reaction Details  Report a problem with these data
Target
5-hydroxytryptamine receptor 1B
Ligand
BDBM50016737
Substrate
n/a
Meas. Tech.
ChEBML_1806
Ki
3970±n/a nM
Citation
 Langlois, M; Gaudy, F; Shen, S; Brémont, B Synthesis of new derivatives of 8-OH-DPAT: Influence of substitution on the aromatic ring on the pharmacological profile Bioorg Med Chem Lett 3:2035-2038 (1993)    Article
Target
Name:
5-hydroxytryptamine receptor 1B
Synonyms:
5-HT-1B | 5-HT1B | 5-hydroxytryptamine receptor 1B (5HT1B) | 5HT1B_RAT | 5ht1b | Htr1b | Serotonin 1 (5-HT1) receptor | Serotonin 1B/1D receptor | Serotonin receptor 1B
Type:
Protein
Mol. Mass.:
43173.33
Organism:
Rattus norvegicus (Rat)
Description:
P28564
Residue:
386
Sequence:
MEEQGIQCAPPPPATSQTGVPLANLSHNCSADDYIYQDSIALPWKVLLVALLALITLATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQVVCDFWLSSDITCCTASIMHLCVIALDRYWAITDAVDYSAKRTPKRAAIMIVLVWVFSISISLPPFFWRQAKAEEEVLDCFVNTDHVLYTVYSTVGAFYLPTLLLIALYGRIYVEARSRILKQTPNKTGKRLTRAQLITDSPGSTSSVTSINSRVPEVPSESGSPVYVNQVKVRVSDALLEKKKLMAARERKATKTLGIILGAFIVCWLPFFIISLVMPICKDACWFHMAIFDFFNWLGYLNSLINPIIYTMSNEDFKQAFHKLIRFKCTG
  
Inhibitor
Name:
BDBM50016737
Synonyms:
(8-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-dipropyl-amine | CHEMBL11760
Type:
Small organic molecule
Emp. Form.:
C17H27NO
Mol. Mass.:
261.4024
SMILES:
CCCN(CCC)C1CCc2cccc(OC)c2C1
Structure:
Search PDB for entries with ligand similarity: