Reaction Details  Report a problem with these data
Target
5-hydroxytryptamine receptor 1B
Ligand
BDBM50280935
Substrate
n/a
Meas. Tech.
ChEBML_1806
Ki
76±n/a nM
Citation
 Langlois, M; Gaudy, F; Shen, S; Brémont, B Synthesis of new derivatives of 8-OH-DPAT: Influence of substitution on the aromatic ring on the pharmacological profile Bioorg Med Chem Lett 3:2035-2038 (1993)    Article
Target
Name:
5-hydroxytryptamine receptor 1B
Synonyms:
5-HT-1B | 5-HT1B | 5-hydroxytryptamine receptor 1B (5HT1B) | 5HT1B_RAT | 5ht1b | Htr1b | Serotonin 1 (5-HT1) receptor | Serotonin 1B/1D receptor | Serotonin receptor 1B
Type:
Protein
Mol. Mass.:
43173.33
Organism:
Rattus norvegicus (Rat)
Description:
P28564
Residue:
386
Sequence:
MEEQGIQCAPPPPATSQTGVPLANLSHNCSADDYIYQDSIALPWKVLLVALLALITLATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQVVCDFWLSSDITCCTASIMHLCVIALDRYWAITDAVDYSAKRTPKRAAIMIVLVWVFSISISLPPFFWRQAKAEEEVLDCFVNTDHVLYTVYSTVGAFYLPTLLLIALYGRIYVEARSRILKQTPNKTGKRLTRAQLITDSPGSTSSVTSINSRVPEVPSESGSPVYVNQVKVRVSDALLEKKKLMAARERKATKTLGIILGAFIVCWLPFFIISLVMPICKDACWFHMAIFDFFNWLGYLNSLINPIIYTMSNEDFKQAFHKLIRFKCTG
  
Inhibitor
Name:
BDBM50280935
Synonyms:
10-Methoxy-1,2,3,4-tetrahydro-phenanthren-2-ylamine | CHEMBL304210
Type:
Small organic molecule
Emp. Form.:
C15H17NO
Mol. Mass.:
227.3016
SMILES:
COc1cc2ccccc2c2CCC(N)Cc12
Structure:
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