Reaction Details  Report a problem with these data
Target
Type-1 angiotensin II receptor B
Ligand
BDBM50282313
Substrate
n/a
Meas. Tech.
ChEMBL_34944 (CHEMBL647787)
Ki
33±n/a nM
Citation
 Lloyd, J; Ryono, DE; Bird, JE; Buote, J; Delaney, CL; Dejneka, T; Dickinson, KE; Moreland, S; Normandin, DE; Skwish, S; Spitzmiller, ER; Waldron, TL Quinoline-4-carboxylic acids as angiotensin II receptor antagonists Bioorg Med Chem Lett 4:195-200 (1994)    Article
Target
Name:
Type-1 angiotensin II receptor B
Synonyms:
AGTRB_RAT | AT3 | Agtr1 | Agtr1b | Angiotensin II AT1B | Angiotensin II receptor (AT-1) type-1 | Angiotensin II type 1b (AT-1b) receptor | At1b | Type-1B angiotensin II receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
40929.44
Organism:
RAT
Description:
Angiotensin II AT1B 0 RAT::P29089
Residue:
359
Sequence:
MTLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIYRNVYFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFVFPFLIILTSYTLIWKALKKAYKIQKNTPRNDDIFRIIMAIVLFFFFSWVPHQIFTFLDVLIQLGIIRDCEIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPTAKSHAGLSTKMSTLSYRPSDNMSSSAKKSASFFEVE
  
Inhibitor
Name:
BDBM50282313
Synonyms:
2-Cyclopropyl-6-methoxy-3-[2'-(2H-tetrazol-5-yl)-biphenyl-4-yloxy]-quinoline-4-carboxylic acid | CHEMBL64220
Type:
Small organic molecule
Emp. Form.:
C27H21N5O4
Mol. Mass.:
479.4867
SMILES:
COc1ccc2nc(C3CC3)c(Oc3ccc(cc3)-c3ccccc3-c3nnn[nH]3)c(C(O)=O)c2c1
Structure:
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