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Target
Beta-lactamase TEM
Ligand
BDBM26142
Substrate
n/a
Meas. Tech.
ChEBML_164508
Ki
29800±n/a nM
Citation
 Martin, R; Gold, M; Jones, J Inhibition of the RTEM-1 β-lactamase by boronic acids Bioorg Med Chem Lett 4:1229-1234 (1994)    Article
Target
Name:
Beta-lactamase TEM
Synonyms:
BLAT_ECOLX | Bacterial beta-lactamase TEM | Beta-lactamase (TEM-1) | Beta-lactamase TEM | Beta-lactamase TEM-1 | Beta-lactamase TEM-1b | Beta-lactamase TEM1D | Beta-lactamase TEM1E | Beta-lactamase TEM1F | TEM beta lactamase | TEM extended-spectrum beta-lactamase | TEM-1 beta-lactamase | bla
Type:
Enzyme
Mol. Mass.:
31512.33
Organism:
Escherichia coli
Description:
P62593
Residue:
286
Sequence:
MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW
  
Inhibitor
Name:
BDBM26142
Synonyms:
(2-phenylethyl)boranediol | Alkylboronic Acid, 21
Type:
Small organic molecule
Emp. Form.:
C8H11BO2
Mol. Mass.:
149.983
SMILES:
OB(O)CCc1ccccc1
Structure:
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