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Target
Type-2 angiotensin II receptor
Ligand
BDBM50284117
Substrate
n/a
Meas. Tech.
ChEMBL_35433 (CHEMBL643793)
IC50
15000±n/a nM
Citation
 Rivero, RA; Greenlee, WJ; Chang, RS Substituted 1,3-benzodioxole & 1,3-benzodithiole -2- carboxylates and their tetrazole analogs with potent binding affinity to the angiotensin II AT1 receptor Bioorg Med Chem Lett 4:747-750 (1994)    Article
Target
Name:
Type-2 angiotensin II receptor
Synonyms:
AGTR2_RAT | AT2 | Agtr2 | Angiotensin II AT2 | Angiotensin II receptor | Angiotensin II type 2 (AT-2) receptor | Type-2 angiotensin II receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
41346.62
Organism:
RAT
Description:
Angiotensin II AT2 0 0::P35351
Residue:
363
Sequence:
MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS
  
Inhibitor
Name:
BDBM50284117
Synonyms:
7-Methyl-3-[2-phenyl-2-(2H-tetrazol-5-yl)-benzo[1,3]dithiol-5-ylmethyl]-2-propyl-3H-imidazo[4,5-b]pyridine | CHEMBL352042
Type:
Small organic molecule
Emp. Form.:
C25H23N7S2
Mol. Mass.:
485.627
SMILES:
CCCc1nc2c(C)ccnc2n1Cc1ccc2SC(Sc2c1)(c1nnn[nH]1)c1ccccc1
Structure:
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