Reaction Details  Report a problem with these data
Target
5-hydroxytryptamine receptor 5A
Ligand
BDBM50288783
Substrate
n/a
Meas. Tech.
ChEBML_1530
Ki
431±n/a nM
Citation
 Appelberg, U; Mohell, N; Hacksell, U Derivatives of 2-arylcyclopropylamine: Synthesis and interactions with 5-HT1A receptors. Bioorg Med Chem Lett 6:415-420 (1996)    Article
Target
Name:
5-hydroxytryptamine receptor 5A
Synonyms:
5-HT-5A | 5-HT5a | 5-hydroxytryptamine receptor 5A | 5HT5A_RAT | 5ht5a | Htr5a | REC17 | Serotonin (5-HT) receptor | Serotonin receptor 5A
Type:
Enzyme Catalytic Domain
Mol. Mass.:
40684.21
Organism:
RAT
Description:
5-HT5a HTR5A RAT::P35364
Residue:
357
Sequence:
MDLPINLTSFSLSTPSTLEPNRSLDTEALRTSQSFLSAFRVLVLTLLGFLAAATFTWNLLVLATILRVRTFHRVPHNLVASMAISDVLVAVLVMPLSLVHELSGRRWQLGRRLCQLWIACDVLCCTASIWNVTAIALDRYWSITRHLEYTLRARKRVSNVMILLTWALSAVISLAPLLFGWGETYSELSEECQVSREPSYTVFSTVGAFYLPLCVVLFVYWKIYKAAKFRMGSRKTNSVSPIPEAVEVKDASQHPQMVFTVRHATVTFQTEGDTWREQKEQRAALMVGILIGVFVLCWFPFFVTELISPLCSWDIPALWKSIFLWLGYSNSFFNPLIYTAFNRSYSSAFKVFFSKQQ
  
Inhibitor
Name:
BDBM50288783
Synonyms:
CHEMBL423527 | Diethyl-[(1S,2S)-2-(2-methoxy-phenyl)-cyclopropylmethyl]-amine
Type:
Small organic molecule
Emp. Form.:
C15H23NO
Mol. Mass.:
233.3492
SMILES:
CCN(CC)C[C@H]1C[C@@H]1c1ccccc1OC
Structure:
Search PDB for entries with ligand similarity: