Reaction Details  Report a problem with these data
Target
Melatonin receptor type 1B
Ligand
BDBM50290235
Substrate
n/a
Meas. Tech.
ChEBML_105267
Ki
23±n/a nM
Citation
 Li, PK; Chu, GH; Gillen, ML; Parekh, T; Witt-Enderby, PA The development of a charged melatonin receptor ligand Bioorg Med Chem Lett 7:2409-2414 (1997)    Article
Target
Name:
Melatonin receptor type 1B
Synonyms:
MTNR1B | MTR1B_HUMAN | Mel-1B-R | Mel1b melatonin receptor | Melatonin 1B | Melatonin receptor | Melatonin receptor type 1B | Melatonin receptor type 2 (MT2)
Type:
Enzyme
Mol. Mass.:
40203.54
Organism:
Homo sapiens (Human)
Description:
P49286
Residue:
362
Sequence:
MSENGSFANCCEAGGWAVRPGWSGAGSARPSRTPRPPWVAPALSAVLIVTTAVDVVGNLLVILSVLRNRKLRNAGNLFLVSLALADLVVAFYPYPLILVAIFYDGWALGEEHCKASAFVMGLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRWHTPLHICLIWLLTVVALLPNFFVGSLEYDPRIYSCTFIQTASTQYTAAVVVIHFLLPIAVVSFCYLRIWVLVLQARRKAKPESRLCLKPSDLRSFLTMFVVFVIFAICWAPLNCIGLAVAINPQEMAPQIPEGLFVTSYLLAYFNSCLNAIVYGLLNQNFRREYKRILLALWNPRHCIQDASKGSHAEGLQSPAPPIIGVQHQADAL
  
Inhibitor
Name:
BDBM50290235
Synonyms:
CHEMBL78338 | {2-[7-Methoxy-1-(2-propionylamino-ethyl)-naphthalen-2-yloxy]-ethyl}-trimethyl-ammonium; iodide
Type:
Small organic molecule
Emp. Form.:
C21H31N2O3
Mol. Mass.:
359.4819
SMILES:
CCC(=O)NCCc1c(OCC[N+](C)(C)C)ccc2ccc(OC)cc12
Structure:
Search PDB for entries with ligand similarity: