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Target
Muscarinic acetylcholine receptor M1
Ligand
BDBM50291551
Substrate
n/a
Meas. Tech.
ChEBML_138345
IC50
1300±n/a nM
Citation
 Conti, P; Dallanoce, C; Amici, MD; Micheli, CD; Ebert, B Synthesis and binding affinity of new muscarinic ligands structurally related to oxotremorine Bioorg Med Chem Lett 7:1033-1036 (1997)    Article
Target
Name:
Muscarinic acetylcholine receptor M1
Synonyms:
ACM1_RAT | Cholinergic, muscarinic M1 | Chrm-1 | Chrm1 | cholinergic receptor, muscarinic 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
51390.46
Organism:
RAT
Description:
P08482
Residue:
460
Sequence:
MNTSVPPAVSPNITVLAPGKGPWQVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVNNYFLLSLACADLIIGTFSMNLYTTYLLMGHWALGTLACDLWLALDYVASNASVMNLLLISFDRYFSVTRPLSYRAKRTPRRAALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYIQFLSQPIITFGTAMAAFYLPVTVMCTLYWRIYRETENRARELAALQGSETPGKGGGSSSSSERSQPGAEGSPESPPGRCCRCCRAPRLLQAYSWKEEEEEDEGSMESLTSSEGEEPGSEVVIKMPMVDSEAQAPTKQPPKSSPNTVKRPTKKGRDRGGKGQKPRGKEQLAKRKTFSLVKEKKAARTLSAILLAFILTWTPYNIMVLVSTFCKDCVPETLWELGYWLCYVNSTVNPMCYALCNKAFRDTFRLLLLCRWDKRRWRKIPKRPGSVHRTPSRQC
  
Inhibitor
Name:
BDBM50291551
Synonyms:
CHEMBL274329 | Trimethyl-[4-(3-oxo-isoxazolidin-2-yl)-but-2-ynyl]-ammonium
Type:
Small organic molecule
Emp. Form.:
C10H17N2O2
Mol. Mass.:
197.2536
SMILES:
C[N+](C)(C)CC#CCN1OCCC1=O
Structure:
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