Reaction Details  Report a problem with these data
Target
Leukotriene B4 receptor 1
Ligand
BDBM50292405
Substrate
n/a
Meas. Tech.
ChEMBL_485590 (CHEMBL1017343)
IC50
15600±n/a nM
Citation
 Chan, GW; Mong, S; Hemling, ME; Freyer, AJ; Offen, PH; DeBrosse, CW; Sarau, HM; Westley, JW New Leukotriene B4 Receptor Antagonist: Leucettamine A and Related Imidazole Alkaloids from the Marine Sponge Leucetta microraphis J Nat Prod 56:116-121 (1993) [PubMed]  Article
Target
Name:
Leukotriene B4 receptor 1
Synonyms:
BLT | BLT1 | BLTR | CMKRL1 | Chemoattractant receptor-like 1 | G-protein coupled receptor 16 | GPR16 | LT4R1_HUMAN | LTB4-R 1 | LTB4R | Leukotriene B4 R1 | Leukotriene B4 receptor | Leukotriene B4 receptor 1 | P2RY7 | P2Y purinoceptor 7 | P2Y7
Type:
Enzyme Catalytic Domain
Mol. Mass.:
37582.68
Organism:
Homo sapiens (Human)
Description:
Q15722
Residue:
352
Sequence:
MNTTSSAAPPSLGVEFISLLAIILLSVALAVGLPGNSFVVWSILKRMQKRSVTALMVLNLALADLAVLLTAPFFLHFLAQGTWSFGLAGCRLCHYVCGVSMYASVLLITAMSLDRSLAVARPFVSQKLRTKAMARRVLAGIWVLSFLLATPVLAYRTVVPWKTNMSLCFPRYPSEGHRAFHLIFEAVTGFLLPFLAVVASYSDIGRRLQARRFRRSRRTGRLVVLIILTFAAFWLPYHVVNLAEAGRALAGQAAGLGLVGKRLSLARNVLIALAFLSSSVNPVLYACAGGGLLRSAGVGFVAKLLEGTGSEASSTRRGGSLGQTARSGPAALEPGPSESLTASSPLKLNELN
  
Inhibitor
Name:
BDBM50292405
Synonyms:
CHEMBL485054 | leucettamidine
Type:
Small organic molecule
Emp. Form.:
C25H24N6O5
Mol. Mass.:
488.4953
SMILES:
CN1C(=N)N(C)\C(=N\c2nc(Cc3ccc4OCOc4c3)c(Cc3ccc4OCOc4c3)n2C)C1=O
Structure:
Search PDB for entries with ligand similarity: