Reaction Details  Report a problem with these data
Target
Prostaglandin D2 receptor
Ligand
BDBM50296851
Substrate
n/a
Meas. Tech.
ChEMBL_582683 (CHEMBL1051057)
Ki
>10000±n/a nM
Citation
 Sandham, DA; Adcock, C; Bala, K; Barker, L; Brown, Z; Dubois, G; Budd, D; Cox, B; Fairhurst, RA; Furegati, M; Leblanc, C; Manini, J; Profit, R; Reilly, J; Stringer, R; Schmidt, A; Turner, KL; Watson, SJ; Willis, J; Williams, G; Wilson, C 7-Azaindole-3-acetic acid derivatives: potent and selective CRTh2 receptor antagonists. Bioorg Med Chem Lett 19:4794-8 (2009) [PubMed]  Article
Target
Name:
Prostaglandin D2 receptor
Synonyms:
PD2R_HUMAN | PTGDR | Prostaglandin D2 | Prostaglandin D2 receptor | Prostanoid DP receptor
Type:
Enzyme
Mol. Mass.:
40288.87
Organism:
Homo sapiens (Human)
Description:
Q13258
Residue:
359
Sequence:
MKSPFYRCQNTTSVEKGNSAVMGGVLFSTGLLGNLLALGLLARSGLGWCSRRPLRPLPSVFYMLVCGLTVTDLLGKCLLSPVVLAAYAQNRSLRVLAPALDNSLCQAFAFFMSFFGLSSTLQLLAMALECWLSLGHPFFYRRHITLRLGALVAPVVSAFSLAFCALPFMGFGKFVQYCPGTWCFIQMVHEEGSLSVLGYSVLYSSLMALLVLATVLCNLGAMRNLYAMHRRLQRHPRSCTRDCAEPRADGREASPQPLEELDHLLLLALMTVLFTMCSLPVIYRAYYGAFKDVKEKNRTSEEAEDLRALRFLSVISIVDPWIFIIFRSPVFRIFFHKIFIRPLRYRSRCSNSTNMESSL
  
Inhibitor
Name:
BDBM50296851
Synonyms:
2-(1-(4-chlorophenylsulfonyl)-2-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)acetic acid | CHEMBL561539
Type:
Small organic molecule
Emp. Form.:
C16H13ClN2O4S
Mol. Mass.:
364.803
SMILES:
Cc1c(CC(O)=O)c2cccnc2n1S(=O)(=O)c1ccc(Cl)cc1
Structure:
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