Reaction Details  Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM50301319
Substrate
n/a
Meas. Tech.
ChEMBL_599308 (CHEMBL1041036)
Ki
62±n/a nM
Citation
 Worm, K; Weaver, DG; Green, RC; Saeui, CT; Dulay, DM; Barker, WM; Cassel, JA; Stabley, GJ; DeHaven, RN; LaBuda, CJ; Koblish, M; Brogdon, BL; Smith, SA; Dolle, RE Discovery of N-(3-(morpholinomethyl)-phenyl)-amides as potent and selective CB2 agonists. Bioorg Med Chem Lett 19:5004-8 (2009) [PubMed]  Article
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM50301319
Synonyms:
4-methyl-3-(3-morpholinopropyl)-N-((1S,4R)-1,3,3-trimethylbicyclo[2.2.1]heptan-2-yl)benzamide | CHEMBL583654
Type:
Small organic molecule
Emp. Form.:
C25H38N2O2
Mol. Mass.:
398.5814
SMILES:
Cc1ccc(cc1CCCN1CCOCC1)C(=O)NC1[C@@]2(C)CC[C@H](C2)C1(C)C |r|
Structure:
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