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Target
Cannabinoid receptor 2
Ligand
BDBM50312841
Substrate
n/a
Meas. Tech.
ChEMBL_615860 (CHEMBL1101970)
Ki
2.3±n/a nM
Citation
 Fujinaga, M; Kumata, K; Yanamoto, K; Kawamura, K; Yamasaki, T; Yui, J; Hatori, A; Ogawa, M; Yoshida, Y; Nengaki, N; Maeda, J; Zhang, MR Radiosynthesis of novel carbon-11-labeled triaryl ligands for cannabinoid-type 2 receptor. Bioorg Med Chem Lett 20:1565-8 (2010) [PubMed]  Article
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CNR2_RAT | Cannabinoid CB2 receptor | Cannabinoid receptor | Cnr2 | rCB2
Type:
Enzyme
Mol. Mass.:
39366.68
Organism:
Rattus norvegicus (Rat)
Description:
Q9QZN9
Residue:
360
Sequence:
MAGCRELELTNGSNGGLEFNPMKEYMILSDAQQIAVAVLCTLMGLLSALENVAVLYLILSSQRLRRKPSYLFIGSLAGADFLASVIFACNFVIFHVFHGVDSRNIFLLKIGSVTMTFTASVGSLLLTAVDRYLCLCYPPTYKALVTRGRALVALGVMWVLSALISYLPLMGWTCCPSPCSELFPLIPNDYLLGWLLFIAILFSGIIYTYGYVLWKAHQHVASLAEHQDRQVPGIARMRLDVRLAKTLGLVMAVLLICWFPALALMGHSLVTTLSDKVKEAFAFCSMLCLVNSMINPIIYALRSGEIRSAAQHCLTGWKKYLQGLGSEGKEEAPKSSVTETEAEVKTTTGPGSRTPGCSNC
  
Inhibitor
Name:
BDBM50312841
Synonyms:
CHEMBL1081609 | US9139546, 30 | [11C](3',5'-dichloro-2-hydroxy-6-methoxybiphenyl-4-yl)(thiophen-2-yl)methanone
Type:
Small organic molecule
Emp. Form.:
C18H12Cl2O3S
Mol. Mass.:
379.257
SMILES:
COc1cc(cc(O)c1-c1cc(Cl)cc(Cl)c1)C(=O)c1cccs1
Structure:
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