Target

Ligand

Substrate

Meas. Tech.

ChEMBL_643889 (CHEMBL1211788)

Citation

 Cai, J; Baugh, M; Black, D; Long, C; Jonathan Bennett, D; Dempster, M; Fradera, X; Gillespie, J; Andrews, F; Boucharens, S; Bruin, J; Cameron, KS; Cumming, I; Hamilton, W; Jones, PS; Kaptein, A; Kinghorn, E; Maidment, M; Martin, I; Mitchell, A; Rankovic, Z; Robinson, J; Scullion, P; Uitdehaag, JC; Vink, P; Westwood, P; van Zeeland, M; van Berkom, L; Bastiani, M; Meulemans, T 6-Phenyl-1H-imidazo[4,5-c]pyridine-4-carbonitrile as cathepsin S inhibitors. Bioorg Med Chem Lett 20:4350-4 (2010) [PubMed]  Article

More Info.:

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Name:

Cathepsin S

Synonyms:

CATS_HUMAN | CTSS | Cathepsin S (Cat S) | cathepsin S preproprotein

Type:

Protein

Mol. Mass.:

37507.38

Organism:

Homo sapiens (Human)

Description:

P25774

Residue:

331

Sequence:

MKRLVCVLLVCSSAVAQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVMLHNLEHSMGMHSYDLGMNHLGDMTSEEVMSLMSSLRVPSQWQRNITYKSNPNRILPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEI

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Name:

BDBM50323263

Synonyms:

1-(2-(dimethylamino)ethyl)-6-(4-ethoxy-3-(trifluoromethyl)phenyl)-1H-imidazo[4,5-c]pyridine-4-carbonitrile | CHEMBL1208849

Type:

Small organic molecule

Emp. Form.:

C20H20F3N5O

Mol. Mass.:

403.4009

SMILES:

CCOc1ccc(cc1C(F)(F)F)-c1cc2n(CCN(C)C)cnc2c(n1)C#N

Structure:

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