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Target
Carbonic anhydrase
Ligand
BDBM10887
Substrate
n/a
Meas. Tech.
ChEMBL_700659 (CHEMBL1645698)
Ki
367±n/a nM
Citation
 Bertucci, A; Innocenti, A; Scozzafava, A; Tambutté, S; Zoccola, D; Supuran, CT Carbonic anhydrase inhibitors. Inhibition studies with anions and sulfonamides of a new cytosolic enzyme from the scleractinian coral Stylophora pistillata. Bioorg Med Chem Lett 21:710-4 (2011) [PubMed]  Article
Target
Name:
Carbonic anhydrase
Synonyms:
n/a
Type:
PROTEIN
Mol. Mass.:
35119.71
Organism:
Stylophora pistillata
Description:
ChEMBL_700659
Residue:
316
Sequence:
MYFLWLISMIAAAMCQEYGYMSEQGVPTPSNWSKVFPLCGGKFQSPINIETKKVKKKSYPDLKISFDNPCGRVTGELLNAGHSPVVNIDSSKGGAKLSGGPLDCDEYALQQFHFHFGCENSRGSEHLIDSQAFPAQLHLVFFNKKYETFQNAVDKPDGLAVLGVLITATCPGNRVLGSFAKKLTKIIEEGASANVTAVDGIKLNYLMPYNNKQGDEDEDDEDIAGDDPDAVEEEEVDAKKKIKYYTYKGSLTTPPCYESVTWIVFKDKIKISNTQLKKFRKLKAQYGGAPGLMCDNIRPVQPLHKRKVYSVLSSRE
  
Inhibitor
Name:
BDBM10887
Synonyms:
Sulfamate 7 | Topiramate (TPM) | US11535599, Example topiramate | [(1R,2S,6S,9R)-4,4,11,11-tetramethyl-3,5,7,10,12-pentaoxatricyclo[7.3.0.0^{2,6}]dodecan-6-yl]methyl sulfamate
Type:
Small organic molecule
Emp. Form.:
C12H21NO8S
Mol. Mass.:
339.362
SMILES:
CC1(C)O[C@@H]2CO[C@@]3(COS(N)(=O)=O)OC(C)(C)O[C@H]3[C@@H]2O1 |r|
Structure:
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