Reaction Details  Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM50284000
Substrate
n/a
Meas. Tech.
ChEMBL_717853 (CHEMBL1670561)
Ki
2.9±n/a nM
Citation
 Brogi, S; Corelli, F; Di Marzo, V; Ligresti, A; Mugnaini, C; Pasquini, S; Tafi, A Three-dimensional quantitative structure-selectivity relationships analysis guided rational design of a highly selective ligand for the cannabinoid receptor 2. Eur J Med Chem 46:547-55 (2011) [PubMed]  Article
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM50284000
Synonyms:
(2-Methyl-1-pentyl-1H-indol-3-yl)-naphthalen-1-yl-methanone | (2-Methyl-1-pentyl-1H-indol-3-yl)-naphthalen-1-yl-methanone (JWH-018) | (2-methyl-1-pentyl-1H-indol-3-yl)(naphthalen-1-yl)methanone | CHEMBL306529 | JWH-007
Type:
Small organic molecule
Emp. Form.:
C25H25NO
Mol. Mass.:
355.4721
SMILES:
CCCCCn1c(C)c(C(=O)c2cccc3ccccc23)c2ccccc12
Structure:
Search PDB for entries with ligand similarity: