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Target
Superoxide dismutase [Cu-Zn]
Ligand
BDBM50336562
Substrate
n/a
Meas. Tech.
ChEMBL_725379 (CHEMBL1676902)
IC50
96600±n/a nM
Citation
 Sánchez-Moreno, M; Sanz, AM; Gómez-Contreras, F; Navarro, P; Marín, C; Ramírez-Macias, I; Rosales, MJ; Olmo, F; Garcia-Aranda, I; Campayo, L; Cano, C; Arrebola, F; Yunta, MJ In vivo trypanosomicidal activity of imidazole- or pyrazole-based benzo[g]phthalazine derivatives against acute and chronic phases of Chagas disease. J Med Chem 54:970-9 (2011) [PubMed]  Article
Target
Name:
Superoxide dismutase [Cu-Zn]
Synonyms:
SOD1 | SODC_HUMAN | Superoxide dismutase
Type:
PROTEIN
Mol. Mass.:
15933.55
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1444880
Residue:
154
Sequence:
MATKAVCVLKGDGPVQGIINFEQKESNGPVKVWGSIKGLTEGLHGFHVHEFGDNTAGCTSAGPHFNPLSRKHGGPKDEERHVGDLGNVTADKDGVADVSIEDSVISLSGDHCIIGRTLVVHEKADDLGKGGNEESTKTGNAGSRLACGVIGIAQ
  
Inhibitor
Name:
BDBM50336562
Synonyms:
1,4-Bis(3'-pyrazolylamino)benzo[g]phthalazine | CHEMBL1672028
Type:
Small organic molecule
Emp. Form.:
C18H14N8
Mol. Mass.:
342.3574
SMILES:
N(c1ccn[nH]1)c1nnc(Nc2ccn[nH]2)c2cc3ccccc3cc12
Structure:
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