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Target
D-alanyl-D-alanine carboxypeptidase
Ligand
BDBM50337102
Substrate
n/a
Meas. Tech.
ChEMBL_718756 (CHEMBL1681054)
Ki
63±n/a nM
Citation
 Woon, EC; Zervosen, A; Sauvage, E; Simmons, KJ; Zivec, M; Inglis, SR; Fishwick, CW; Gobec, S; Charlier, P; Luxen, As Structure Guided Development of Potent Reversibly Binding Penicillin Binding Protein Inhibitors ACS Med Chem Lett 2:219-223 (2011) [PubMed]  Article
Target
Name:
D-alanyl-D-alanine carboxypeptidase
Synonyms:
DAC_ACTSP | dac
Type:
PROTEIN
Mol. Mass.:
54928.46
Organism:
Actinomadura sp. (strain R39)
Description:
ChEMBL_822544
Residue:
538
Sequence:
MKQSSPEPLRPRRTGGRGGARRAAALVTIPLLPMTLLGASPALADASGARLTELREDIDAILEDPALEGAVSGVVVVDTATGEELYSRDGGEQLLPASNMKLFTAAAALEVLGADHSFGTEVAAESAPGRRGEVQDLYLVGRGDPTLSAEDLDAMAAEVAASGVRTVRGDLYADDTWFDSERLVDDWWPEDEPYAYSAQISALTVAHGERFDTGVTEVSVTPAAEGEPADVDLGAAEGYAELDNRAVTGAAGSANTLVIDRPVGTNTIAVTGSLPADAAPVTALRTVDEPAALAGHLFEEALESNGVTVKGDVGLGGVPADWQDAEVLADHTSAELSEILVPFMKFSNNGHAEMLVKSIGQETAGAGTWDAGLVGVEEALSGLGVDTAGLVLNDGSGLSRGNLVTADTVVDLLGQAGSAPWAQTWSASLPVAGESDPFVGGTLANRMRGTAAEGVVEAKTGTMSGVSALSGYVPGPEGELAFSIVNNGHSGPAPLAVQDAIAVRLAEYAGHQAPEGARMMRGPVQGSGELECSWVQAC
  
Inhibitor
Name:
BDBM50337102
Synonyms:
(S)-1-(2-(Diphenylmethyl)benzamido)ethaneboronate | CHEMBL1672910
Type:
Small organic molecule
Emp. Form.:
C22H22BNO3
Mol. Mass.:
359.226
SMILES:
C[C@@H](NC(=O)c1ccccc1C(c1ccccc1)c1ccccc1)B(O)O |r|
Structure:
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