Reaction Details  Report a problem with these data
Target
P2Y purinoceptor 4
Ligand
BDBM50341881
Substrate
n/a
Meas. Tech.
ChEMBL_743276 (CHEMBL1767475)
EC50
1520±n/a nM
Citation
 El-Tayeb, A; Qi, A; Nicholas, RA; Müller, CE Structural modifications of UMP, UDP, and UTP leading to subtype-selective agonists for P2Y2, P2Y4, and P2Y6 receptors. J Med Chem 54:2878-90 (2011) [PubMed]  Article
Target
Name:
P2Y purinoceptor 4
Synonyms:
NRU | P2P | P2RY4 | P2RY4_HUMAN | P2Y purinoceptor 4 | P2Y4 | Pyrimidinergic receptor P2Y4 | UNR | Uridine nucleotide receptor
Type:
PROTEIN
Mol. Mass.:
40977.17
Organism:
Homo sapiens (Human)
Description:
ChEMBL_751027
Residue:
365
Sequence:
MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL
  
Inhibitor
Name:
BDBM50341881
Synonyms:
2-methylthio-1-beta-D-ribofuranosylpyrimidine-4-one-5'-diphosphate | CHEMBL1767410
Type:
Small organic molecule
Emp. Form.:
C10H16N2O11P2S
Mol. Mass.:
434.253
SMILES:
CSc1nc(=O)ccn1[C@@H]1O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O |r|
Structure:
Search PDB for entries with ligand similarity: