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Target
P2Y purinoceptor 4
Ligand
BDBM50345483
Substrate
n/a
Meas. Tech.
ChEMBL_751027 (CHEMBL1786812)
EC50
2110±n/a nM
Citation
 Maruoka, H; Jayasekara, MP; Barrett, MO; Franklin, DA; de Castro, S; Kim, N; Costanzi, S; Harden, TK; Jacobson, KA Pyrimidine nucleotides with 4-alkyloxyimino and terminal tetraphosphated-ester modifications as selective agonists of the P2Y(4) receptor. J Med Chem 54:4018-33 (2011) [PubMed]  Article
Target
Name:
P2Y purinoceptor 4
Synonyms:
NRU | P2P | P2RY4 | P2RY4_HUMAN | P2Y purinoceptor 4 | P2Y4 | Pyrimidinergic receptor P2Y4 | UNR | Uridine nucleotide receptor
Type:
PROTEIN
Mol. Mass.:
40977.17
Organism:
Homo sapiens (Human)
Description:
ChEMBL_751027
Residue:
365
Sequence:
MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL
  
Inhibitor
Name:
BDBM50345483
Synonyms:
CHEMBL1784891 | N4-t-Butyloxycytidine-5'-triphosphate
Type:
Small organic molecule
Emp. Form.:
C13H24N3O15P3
Mol. Mass.:
555.262
SMILES:
CC(C)(C)ONc1ccn([C@@H]2O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]2O)c(=O)n1 |r|
Structure:
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