Reaction Details  Report a problem with these data
Target
Casein kinase I isoform alpha
Ligand
BDBM50346236
Substrate
n/a
Meas. Tech.
ChEMBL_749961 (CHEMBL1786938)
IC50
>10000±n/a nM
Citation
 Power, DP; Lozach, O; Meijer, L; Grayson, DH; Connon, SJ Concise synthesis and CDK/GSK inhibitory activity of the missing 9-azapaullones. Bioorg Med Chem Lett 20:4940-4 (2010) [PubMed]  Article
Target
Name:
Casein kinase I isoform alpha
Synonyms:
CK1 | CKI-alpha | CSNK1A1 | KC1A_PIG
Type:
PROTEIN
Mol. Mass.:
14639.55
Organism:
Sus scrofa
Description:
ChEMBL_939731
Residue:
125
Sequence:
GEEVAVKLESQKARHPQLLYESKLYKILQGGVGIPHIRWYGQEKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKY
  
Inhibitor
Name:
BDBM50346236
Synonyms:
9-Benzyl-6-oxo-5,6,7,12-tetrahydro-5,12-diaza-9-azonia-dibenzo[a,e]azulene bromide | CHEMBL1782169
Type:
Small organic molecule
Emp. Form.:
C22H18N3O
Mol. Mass.:
340.3973
SMILES:
O=C1Cc2c([nH+]c3ccn(Cc4ccccc4)cc23)-c2ccccc2N1
Structure:
Search PDB for entries with ligand similarity: