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Target
Casein kinase I isoform alpha
Ligand
BDBM50346237
Substrate
n/a
Meas. Tech.
ChEMBL_749961 (CHEMBL1786938)
IC50
>10000±n/a nM
Citation
 Power, DP; Lozach, O; Meijer, L; Grayson, DH; Connon, SJ Concise synthesis and CDK/GSK inhibitory activity of the missing 9-azapaullones. Bioorg Med Chem Lett 20:4940-4 (2010) [PubMed]  Article
Target
Name:
Casein kinase I isoform alpha
Synonyms:
CK1 | CKI-alpha | CSNK1A1 | KC1A_PIG
Type:
PROTEIN
Mol. Mass.:
14639.55
Organism:
Sus scrofa
Description:
ChEMBL_939731
Residue:
125
Sequence:
GEEVAVKLESQKARHPQLLYESKLYKILQGGVGIPHIRWYGQEKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKY
  
Inhibitor
Name:
BDBM50346237
Synonyms:
9-Oxy-5,12-dihydro-7H-5,9,12-triaza-dibenzo[a,e]azulen-6-one | CHEMBL1782170
Type:
Small organic molecule
Emp. Form.:
C15H11N3O2
Mol. Mass.:
265.2667
SMILES:
[O-][n+]1ccc2[nH]c-3c(CC(=O)Nc4ccccc-34)c2c1
Structure:
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