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Target
Adenosine kinase
Ligand
BDBM50350196
Substrate
n/a
Meas. Tech.
ChEMBL_761462 (CHEMBL1817183)
IC50
>10000±n/a nM
Citation
 Bourderioux, A; Naus, P; Perlíková, P; Pohl, R; Pichová, I; Votruba, I; Dzubák, P; Konecný, P; Hajdúch, M; Stray, KM; Wang, T; Ray, AS; Feng, JY; Birkus, G; Cihlar, T; Hocek, M Synthesis and significant cytostatic activity of 7-hetaryl-7-deazaadenosines. J Med Chem 54:5498-507 (2011) [PubMed]  Article
Target
Name:
Adenosine kinase
Synonyms:
ADK | ADK_HUMAN
Type:
PROTEIN
Mol. Mass.:
40545.97
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1467841
Residue:
362
Sequence:
MAAAEEEPKPKKLKVEAPQALRENILFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDKHKELFDELVKKFKVEYHAGGSTQNSIKVAQWMIQQPHKAATFFGCIGIDKFGEILKRKAAEAHVDAHYYEQNEQPTGTCAACITGDNRSLIANLAAANCYKKEKHLDLEKNWMLVEKARVCYIAGFFLTVSPESVLKVAHHASENNRIFTLNLSAPFISQFYKESLMKVMPYVDILFGNETEAATFAREQGFETKDIKEIAKKTQALPKMNSKRQRIVIFTQGRDDTIMATESEVTAFAVLDQDQKEIIDTNGAGDAFVGGFLSQLVSDKPLTECIRAGHYAASIIIRRTGCTFPEKPDFH
  
Inhibitor
Name:
BDBM50350196
Synonyms:
CHEMBL1814764
Type:
Small organic molecule
Emp. Form.:
C18H20N4O4S
Mol. Mass.:
388.441
SMILES:
CSc1ccc(cc1)-c1cn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c2ncnc(N)c12 |r|
Structure:
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