Reaction Details  Report a problem with these data
Target
Sigma non-opioid intracellular receptor 1
Ligand
BDBM50353850
Substrate
n/a
Meas. Tech.
ChEMBL_769360 (CHEMBL1833366)
Ki
92.43±n/a nM
Citation
 Mésangeau, C; Amata, E; Alsharif, W; Seminerio, MJ; Robson, MJ; Matsumoto, RR; Poupaert, JH; McCurdy, CR Synthesis and pharmacological evaluation of indole-based sigma receptor ligands. Eur J Med Chem 46:5154-61 (2011) [PubMed]  Article
Target
Name:
Sigma non-opioid intracellular receptor 1
Synonyms:
Opioid receptor | Oprs1 | SGMR1_RAT | Sigma | Sigma non-opioid intracellular receptor 1 | Sigma opioid receptor | Sigma-1 | Sigmar1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
25266.54
Organism:
RAT
Description:
Q9R0C9
Residue:
223
Sequence:
MPWAVGRRWAWITLFLTIVAVLIQAVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSRLIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSHGHSGRYWAEISDTIISGTFHQWREGTTKSEVYYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPSTLAFALSDTIFSTQDFLTLFYTLRAYARGLRLELTTYLFGQDP
  
Inhibitor
Name:
BDBM50353850
Synonyms:
CHEMBL1831161
Type:
Small organic molecule
Emp. Form.:
C28H37N3
Mol. Mass.:
415.6135
SMILES:
C(CCn1cc(-c2ccccc2)c2ccccc12)CN1CCN(CC1)C1CCCCC1
Structure:
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