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Target
Prostaglandin D2 receptor
Ligand
BDBM50362155
Substrate
n/a
Meas. Tech.
ChEMBL_797761 (CHEMBL1944120)
IC50
>1000±n/a nM
Citation
 Ito, S; Terasaka, T; Zenkoh, T; Matsuda, H; Hayashida, H; Nagata, H; Imamura, Y; Kobayashi, M; Takeuchi, M; Ohta, M Discovery of novel and potent CRTH2 antagonists. Bioorg Med Chem Lett 22:1194-7 (2012) [PubMed]  Article
Target
Name:
Prostaglandin D2 receptor
Synonyms:
PD2R_HUMAN | PTGDR | Prostaglandin D2 | Prostaglandin D2 receptor | Prostanoid DP receptor
Type:
Enzyme
Mol. Mass.:
40288.87
Organism:
Homo sapiens (Human)
Description:
Q13258
Residue:
359
Sequence:
MKSPFYRCQNTTSVEKGNSAVMGGVLFSTGLLGNLLALGLLARSGLGWCSRRPLRPLPSVFYMLVCGLTVTDLLGKCLLSPVVLAAYAQNRSLRVLAPALDNSLCQAFAFFMSFFGLSSTLQLLAMALECWLSLGHPFFYRRHITLRLGALVAPVVSAFSLAFCALPFMGFGKFVQYCPGTWCFIQMVHEEGSLSVLGYSVLYSSLMALLVLATVLCNLGAMRNLYAMHRRLQRHPRSCTRDCAEPRADGREASPQPLEELDHLLLLALMTVLFTMCSLPVIYRAYYGAFKDVKEKNRTSEEAEDLRALRFLSVISIVDPWIFIIFRSPVFRIFFHKIFIRPLRYRSRCSNSTNMESSL
  
Inhibitor
Name:
BDBM50362155
Synonyms:
CHEMBL1941116
Type:
Small organic molecule
Emp. Form.:
C29H27NO4
Mol. Mass.:
453.529
SMILES:
OC(=O)COc1cccc(CCCn2cc(ccc2=O)C(c2ccccc2)c2ccccc2)c1
Structure:
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