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Target
Carbonic anhydrase
Ligand
BDBM26999
Substrate
n/a
Meas. Tech.
ChEMBL_801827 (CHEMBL1947439)
Ki
276±n/a nM
Citation
 Ohradanova, A; Vullo, D; Pastorekova, S; Pastorek, J; Jackson, DJ; Wörheide, G; Supuran, CT Cloning, characterization and sulfonamide inhibition studies of ana-carbonic anhydrase from the living fossil sponge Astrosclera willeyana. Bioorg Med Chem 20:1403-10 (2012) [PubMed]  Article
Target
Name:
Carbonic anhydrase
Synonyms:
Astrosclerin-3
Type:
PROTEIN
Mol. Mass.:
33233.07
Organism:
Astrosclera willeyana
Description:
ChEMBL_801827
Residue:
292
Sequence:
MMAYKVLHFVVISLGLVTLVASRCDFNYYNQRAWLSCPGSQCGGNRQSPINIDTEKTKANNSLIALRFNDYDDPVDGDFENLGTTVEFVPETKDATLTNHLGTYDLLQFHFHWGRDSSEGSEHRIDDEQYSAEIHFVHLKQGASPSDTAGDTFSVVAVLCEAADIPIRGVWAKLSPVPTGHEDSHSVSDLVYTDLLPRNRDYYHYEGSLTTPLCDETVQWFVLKNTIKIPKAFLTMLRRVESDEDGTLLTFNFRNLQRLNGRQVFEFPPDVDNGEDKKRKRRNNRHGRDHHG
  
Inhibitor
Name:
BDBM26999
Synonyms:
4-(1,1-dioxo-1,2-thiazinan-2-yl)benzene-1-sulfonamide | CHEMBL328560 | Contravul | Ospolot | Sulthiame (SLT) | Sulthiame, 2
Type:
Small organic molecule
Emp. Form.:
C10H14N2O4S2
Mol. Mass.:
290.359
SMILES:
NS(=O)(=O)c1ccc(cc1)N1CCCCS1(=O)=O
Structure:
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