Reaction Details  Report a problem with these data
Target
P2Y purinoceptor 2
Ligand
BDBM50366147
Substrate
n/a
Meas. Tech.
ChEMBL_805630 (CHEMBL1960464)
EC50
>20000±n/a nM
Citation
 Van Poecke, S; Barrett, MO; Santhosh Kumar, T; Sinnaeve, D; Martins, JC; Jacobson, KA; Kendall Harden, T; Van Calenbergh, S Synthesis and P2Y2 receptor agonist activities of uridine 5'-phosphonate analogues. Bioorg Med Chem 20:2304-15 (2012) [PubMed]  Article
Target
Name:
P2Y purinoceptor 2
Synonyms:
ATP receptor | P2RU1 | P2RY2 | P2RY2_HUMAN | P2U purinoceptor 1 | P2U1 | P2Y purinoceptor 2 | P2Y2 | Purinergic receptor | Purinergic receptor P2Y2
Type:
PROTEIN
Mol. Mass.:
42299.21
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1455361
Residue:
377
Sequence:
MAADLGPWNDTINGTWDGDELGYRCRFNEDFKYVLLPVSYGVVCVPGLCLNAVALYIFLCRLKTWNASTTYMFHLAVSDALYAASLPLLVYYYARGDHWPFSTVLCKLVRFLFYTNLYCSILFLTCISVHRCLGVLRPLRSLRWGRARYARRVAGAVWVLVLACQAPVLYFVTTSARGGRVTCHDTSAPELFSRFVAYSSVMLGLLFAVPFAVILVCYVLMARRLLKPAYGTSGGLPRAKRKSVRTIAVVLAVFALCFLPFHVTRTLYYSFRSLDLSCHTLNAINMAYKVTRPLASANSCLDPVLYFLAGQRLVRFARDAKPPTGPSPATPARRRLGLRRSDRTDMQRIEDVLGSSEDSRRTESTPAGSENTKDIRL
  
Inhibitor
Name:
BDBM50366147
Synonyms:
CHEMBL1957447
Type:
Small organic molecule
Emp. Form.:
C10H12ClN2O7P
Mol. Mass.:
338.639
SMILES:
O[C@@H]1[C@@H](CCP([O-])([O-])=O)O[C@H]([C@@H]1Cl)n1ccc(=O)[nH]c1=O |r|
Structure:
Search PDB for entries with ligand similarity: