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Target
Gag-Pol polyprotein [489-587]
Ligand
BDBM50279830
Substrate
n/a
Meas. Tech.
ChEMBL_79972 (CHEMBL690410)
Ki
44000±n/a nM
Citation
 McLeod, DA; Brinkworth, RI; Ashley, JA; Janda, KD; Wirsching, P Phosphonamidates and phosphonamidate esters as HIV-1 protease inhibitors Bioorg Med Chem Lett 1:653-658 (1991)    Article
Target
Name:
Gag-Pol polyprotein [489-587]
Synonyms:
Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol
Type:
Enzyme Subunit
Mol. Mass.:
10781.16
Organism:
Human immunodeficiency virus type 1
Description:
P04585[489-587]
Residue:
99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
  
Inhibitor
Name:
BDBM50279830
Synonyms:
((S)-2-Carbamoyl-pyrrolidin-1-yl)-[2-phenyl-1-(2,2,2-trifluoro-acetylamino)-ethyl]-phosphinic acid methyl ester | CHEMBL158393
Type:
Small organic molecule
Emp. Form.:
C16H21F3N3O4P
Mol. Mass.:
407.3246
SMILES:
COP(=O)(C(Cc1ccccc1)NC(=O)C(F)(F)F)N1CCC[C@H]1C(N)=O
Structure:
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