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Target
E-selectin
Ligand
BDBM50421385
Substrate
n/a
Meas. Tech.
ChEBML_199693
IC50
2100000±n/a nM
Citation
 Bamford, MJ; Bird, M; Gore, PM; Holmes, DS; Priest, R; Prodger, JC; Saez, V Synthesis and biological activity of conformationally constrained sialyl Lewis X analogues with reduced carbohydrate character Bioorg Med Chem Lett 6:239-244 (1996)    Article
Target
Name:
E-selectin
Synonyms:
ELAM1 | LYAM2_HUMAN | SELE | Selectin | Selectin E
Type:
PROTEIN
Mol. Mass.:
66642.96
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1438995
Residue:
610
Sequence:
MIASQFLSALTLVLLIKESGAWSYNTSTEAMTYDEASAYCQQRYTHLVAIQNKEEIEYLNSILSYSPSYYWIGIRKVNNVWVWVGTQKPLTEEAKNWAPGEPNNRQKDEDCVEIYIKREKDVGMWNDERCSKKKLALCYTAACTNTSCSGHGECVETINNYTCKCDPGFSGLKCEQIVNCTALESPEHGSLVCSHPLGNFSYNSSCSISCDRGYLPSSMETMQCMSSGEWSAPIPACNVVECDAVTNPANGFVECFQNPGSFPWNTTCTFDCEEGFELMGAQSLQCTSSGNWDNEKPTCKAVTCRAVRQPQNGSVRCSHSPAGEFTFKSSCNFTCEEGFMLQGPAQVECTTQGQWTQQIPVCEAFQCTALSNPERGYMNCLPSASGSFRYGSSCEFSCEQGFVLKGSKRLQCGPTGEWDNEKPTCEAVRCDAVHQPPKGLVRCAHSPIGEFTYKSSCAFSCEEGFELHGSTQLECTSQGQWTEEVPSCQVVKCSSLAVPGKINMSCSGEPVFGTVCKFACPEGWTLNGSAARTCGATGHWSGLLPTCEAPTESNIPLVAGLSAAGLSLLTLAPFLLWLRKCLRKAKKFVPASSCQSLESDGSYQKPSYIL
  
Inhibitor
Name:
BDBM50421385
Synonyms:
CHEMBL2303692
Type:
Small organic molecule
Emp. Form.:
C18H32O13
Mol. Mass.:
456.4389
SMILES:
CC(O[C@@H]1O[C@@H](C)[C@@H](O)[C@H](O)[C@@H]1O)C(C)O[C@@H]1O[C@@H](CO)[C@H](O)[C@H](OCC(O)=O)[C@@H]1O |r|
Structure:
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