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Target
D(4) dopamine receptor
Ligand
BDBM50115716
Substrate
n/a
Meas. Tech.
ChEMBL_63099 (CHEMBL674492)
Ki
12±n/a nM
Citation
 Bergauer, M; Hübner, H; Gmeiner, P 2,4-Disubstituted pyrroles: synthesis, traceless linking and pharmacological investigations leading to the dopamine D4 receptor partial agonist FAUC 356. Bioorg Med Chem Lett 12:1937-40 (2002) [PubMed]
Target
Name:
D(4) dopamine receptor
Synonyms:
D(2C) dopamine receptor | DOPAMINE D4 | DOPAMINE D4.2 | DOPAMINE D4.4 | DRD4 | DRD4_HUMAN | Dopamine D4 receptor
Type:
Enzyme
Mol. Mass.:
48373.19
Organism:
Homo sapiens (Human)
Description:
P21917
Residue:
419
Sequence:
MGNRSTADADGLLAGRGPAAGASAGASAGLAGQGAAALVGGVLLIGAVLAGNSLVCVSVATERALQTPTNSFIVSLAAADLLLALLVLPLFVYSEVQGGAWLLSPRLCDALMAMDVMLCTASIFNLCAISVDRFVAVAVPLRYNRQGGSRRQLLLIGATWLLSAAVAAPVLCGLNDVRGRDPAVCRLEDRDYVVYSSVCSFFLPCPLMLLLYWATFRGLQRWEVARRAKLHGRAPRRPSGPGPPSPTPPAPRLPQDPCGPDCAPPAPGLPRGPCGPDCAPAAPSLPQDPCGPDCAPPAPGLPPDPCGSNCAPPDAVRAAALPPQTPPQTRRRRRAKITGRERKAMRVLPVVVGAFLLCWTPFFVVHITQALCPACSVPPRLVSAVTWLGYVNSALNPVIYTVFNAEFRNVFRKALRACC
  
Inhibitor
Name:
BDBM50115716
Synonyms:
1-Phenyl-4-(4-phenyl-1H-pyrrol-2-ylmethyl)-piperazine | 1-phenyl-4-((4-phenyl-1H-pyrrol-2-yl)methyl)piperazine | CHEMBL60815
Type:
Small organic molecule
Emp. Form.:
C21H23N3
Mol. Mass.:
317.4274
SMILES:
C(N1CCN(CC1)c1ccccc1)c1cc(c[nH]1)-c1ccccc1
Structure:
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