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Target
D(1A) dopamine receptor
Ligand
BDBM50115716
Substrate
n/a
Meas. Tech.
ChEBML_60194
Ki
2100±n/a nM
Citation
 Bergauer, M; Hübner, H; Gmeiner, P 2,4-Disubstituted pyrroles: synthesis, traceless linking and pharmacological investigations leading to the dopamine D4 receptor partial agonist FAUC 356. Bioorg Med Chem Lett 12:1937-40 (2002) [PubMed]
Target
Name:
D(1A) dopamine receptor
Synonyms:
D(1A) dopamine receptor | D1AR | DOPAMINE D1 | DRD1 | DRD1_BOVIN | Dopamine receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49330.65
Organism:
BOVINE
Description:
DOPAMINE D1 DRD1 BOVINE::Q95136
Residue:
446
Sequence:
MRTLNTSTMEGTGLVAERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTGPSEGNATSLGKTINNCDSSLSRTYAISSSLISFYIPVAIMIVTYTRIYRIAQKQIRRISALERAAVHAKNCQTTTGNGNPMECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCGSGETKPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPTTNNAIETVSINNNGAVVFSSHHEPRGSISKDCNVVYLIPHAVGSSEGLKKEEAVGIAKPLEKLSPALSVILDYDTDVSLEKIQPITQNGQHPT
  
Inhibitor
Name:
BDBM50115716
Synonyms:
1-Phenyl-4-(4-phenyl-1H-pyrrol-2-ylmethyl)-piperazine | 1-phenyl-4-((4-phenyl-1H-pyrrol-2-yl)methyl)piperazine | CHEMBL60815
Type:
Small organic molecule
Emp. Form.:
C21H23N3
Mol. Mass.:
317.4274
SMILES:
C(N1CCN(CC1)c1ccccc1)c1cc(c[nH]1)-c1ccccc1
Structure:
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