Reaction Details  Report a problem with these data
Target
5-hydroxytryptamine receptor 3B
Ligand
BDBM50013046
Substrate
n/a
Meas. Tech.
ChEBML_3121
Ki
>1±n/a nM
Citation
 Rizzi, JP; Nagel, AA; Rosen, T; McLean, S; Seeger, T An initial three-component pharmacophore for specific serotonin-3 receptor ligands. J Med Chem 33:2721-5 (1990) [PubMed]
Target
Name:
5-hydroxytryptamine receptor 3B
Synonyms:
5HT3B_MOUSE | Htr3b | Serotonin 3 receptor (5HT3) | Serotonin 3b (5-HT3b) receptor
Type:
PROTEIN
Mol. Mass.:
50317.35
Organism:
Mus musculus
Description:
ChEMBL_3121
Residue:
437
Sequence:
MILLWSCLLVAVVGILGTATPQPGNSSLHRLTRQLLQQYHKEVRPVYNWAEATTVYLDLCVHAVLDVDVQNQKLKTSVWYREVWNDEFLSWNSSLFDEIQEISLPLSALWAPDIIINEFVDVERSPDLPYVYVNSSGTIRNHKPIQVVSACSLQTYAFPFDIQNCSLTFNSILHTVEDIDLGFLRNREDIENDKRAFMNDSEWQLLSVSSTYHIRQSSAGDFAQIRFNVVIRRCPLAYVVSLLIPSIFLMLVDLGSFYLPPNCRARIVFKTNVLVGYTVFRVNMSDEVPRSAGCTPLIGVFFTVCMALLVLSLSKSILLIKFLYEERHSGQERPLMCLQGDSDAEESRLYLGAPRADVTESPVHQEHRVPSDTLKDFWFQFRSINNSLRTRDQIHQKEVEWLAILYRFDQLLFRIYLAVLGLYTVTLCSLWALWSRM
  
Inhibitor
Name:
BDBM50013046
Synonyms:
1-(Thiophen-2-ylmethyl)guanidine | CHEMBL93064 | N-Thiophen-2-ylmethyl-guanidine
Type:
Small organic molecule
Emp. Form.:
C6H9N3S
Mol. Mass.:
155.221
SMILES:
NC(=N)NCc1cccs1
Structure:
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