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Target
D(3) dopamine receptor
Ligand
BDBM50048230
Substrate
n/a
Meas. Tech.
ChEMBL_61949 (CHEMBL671349)
Ki
150±n/a nM
Citation
 Thurkauf, A; Yuan, J; Chen, X; Wasley, JW; Meade, R; Woodruff, KH; Huston, K; Ross, PC 1-Phenyl-3-(aminomethyl)pyrroles as potential antipsychotic agents. Synthesis and dopamine receptor binding. J Med Chem 38:4950-2 (1996) [PubMed]
Target
Name:
D(3) dopamine receptor
Synonyms:
DRD3 | DRD3_CHLAE
Type:
PROTEIN
Mol. Mass.:
44355.59
Organism:
Chlorocebus aethiops
Description:
ChEMBL_105569
Residue:
400
Sequence:
MAPLSQLSGHLNYTCGVENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRVCCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVTLMITAVWVLAFAVSCPLLFGFNTTGDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQQTLSPDRAHLELKRYYSICQDTALGGPGFQERGGELKREERTRNSLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
  
Inhibitor
Name:
BDBM50048230
Synonyms:
1-(1-Phenyl-1H-pyrrol-3-ylmethyl)-4-pyridin-2-yl-piperazine | CHEMBL343466
Type:
Small organic molecule
Emp. Form.:
C20H22N4
Mol. Mass.:
318.4155
SMILES:
C(N1CCN(CC1)c1ccccn1)c1ccn(c1)-c1ccccc1
Structure:
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