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Target
Platelet-activating factor receptor
Ligand
BDBM50055484
Substrate
n/a
Meas. Tech.
ChEMBL_155146 (CHEMBL760187)
IC50
550±n/a nM
Citation
 Sugano, M; Sato, A; Saito, K; Takaishi, S; Matsushita, Y; Iijima, Y Structure-activity relationships of phomactin derivatives as platelet activating factor antagonists. J Med Chem 39:5281-4 (1997) [PubMed]  Article
Target
Name:
Platelet-activating factor receptor
Synonyms:
PAF-R | PTAFR | PTAFR_CAVPO | Platelet activating factor receptor | Platelet-activating factor receptor
Type:
Protein
Mol. Mass.:
39005.63
Organism:
Cavia porcellus
Description:
n/a
Residue:
342
Sequence:
MELNSSSRVDSEFRYTLFPIVYSIIFVLGIIANGYVLWVFARLYPSKKLNEIKIFMVNLTVADLLFLITLPLWIVYYSNQGNWFLPKFLCNLAGCLFFINTYCSVAFLGVITYNRFQAVKYPIKTAQATTRKRGIALSLVIWVAIVAAASYFLVMDSTNVVSNKAGSGNITRCFEHYEKGSKPVLIIHICIVLGFFIVFLLILFCNLVIIHTLLRQPVKQQRNAEVRRRALWMVCTVLAVFVICFVPHHMVQLPWTLAELGMWPSSNHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKFRKHLSEKLNIMRSSQKCSRVTTDTGTEMAIPINHTPVNPIKN
  
Inhibitor
Name:
BDBM50055484
Synonyms:
CHEMBL421954 | Carbonic acid phenyl ester (E)-(1R,3S,5R,12S,13R,16S)-5,9,12,13-tetramethyl-2-oxo-4-oxa-tricyclo[10.3.1.0*3,5*]hexadec-8-en-16-ylmethyl ester
Type:
Small organic molecule
Emp. Form.:
C27H36O5
Mol. Mass.:
440.5717
SMILES:
C[C@@H]1CC[C@@H]2[C@H](COC(=O)Oc3ccccc3)[C@@]1(C)CC\C(C)=C\CC[C@@]1(C)O[C@@H]1C2=O |t:24|
Structure:
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