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Target
Platelet-activating factor receptor
Ligand
BDBM50055493
Substrate
n/a
Meas. Tech.
ChEMBL_155146 (CHEMBL760187)
IC50
130±n/a nM
Citation
 Sugano, M; Sato, A; Saito, K; Takaishi, S; Matsushita, Y; Iijima, Y Structure-activity relationships of phomactin derivatives as platelet activating factor antagonists. J Med Chem 39:5281-4 (1997) [PubMed]  Article
Target
Name:
Platelet-activating factor receptor
Synonyms:
PAF-R | PTAFR | PTAFR_CAVPO | Platelet activating factor receptor | Platelet-activating factor receptor
Type:
Protein
Mol. Mass.:
39005.63
Organism:
Cavia porcellus
Description:
n/a
Residue:
342
Sequence:
MELNSSSRVDSEFRYTLFPIVYSIIFVLGIIANGYVLWVFARLYPSKKLNEIKIFMVNLTVADLLFLITLPLWIVYYSNQGNWFLPKFLCNLAGCLFFINTYCSVAFLGVITYNRFQAVKYPIKTAQATTRKRGIALSLVIWVAIVAAASYFLVMDSTNVVSNKAGSGNITRCFEHYEKGSKPVLIIHICIVLGFFIVFLLILFCNLVIIHTLLRQPVKQQRNAEVRRRALWMVCTVLAVFVICFVPHHMVQLPWTLAELGMWPSSNHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKFRKHLSEKLNIMRSSQKCSRVTTDTGTEMAIPINHTPVNPIKN
  
Inhibitor
Name:
BDBM50055493
Synonyms:
CHEMBL148549 | Carbonic acid (E)-(1R,2R,3R,5R,12S,13R,16S)-2-hydroxy-5,9,12,13-tetramethyl-4-oxa-tricyclo[10.3.1.0*3,5*]hexadec-8-en-16-ylmethyl ester methyl ester
Type:
Small organic molecule
Emp. Form.:
C22H36O5
Mol. Mass.:
380.5182
SMILES:
COC(=O)OC[C@H]1[C@H]2CC[C@@H](C)[C@]1(C)CC\C(C)=C\CC[C@@]1(C)O[C@@H]1[C@@H]2O |t:18|
Structure:
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