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Target
Somatostatin receptor type 3
Ligand
BDBM50369422
Substrate
n/a
Meas. Tech.
ChEMBL_200502 (CHEMBL803847)
IC50
539±n/a nM
Citation
 Hocart, SJ; Jain, R; Murphy, WA; Taylor, JE; Morgan, B; Coy, DH Potent antagonists of somatostatin: synthesis and biology. J Med Chem 41:1146-54 (1998) [PubMed]  Article
Target
Name:
Somatostatin receptor type 3
Synonyms:
SOMATOSTATIN SST3 | SS-3-R | SS3-R | SS3R | SSR-28 | SSR3_HUMAN | SSTR3 | Somatostatin receptor type 3 (SSTR3)
Type:
Protein
Mol. Mass.:
45855.97
Organism:
Homo sapiens (Human)
Description:
P32745
Residue:
418
Sequence:
MDMLHPSSVSTTSEPENASSAWPPDATLGNVSAGPSPAGLAVSGVLIPLVYLVVCVVGLLGNSLVIYVVLRHTASPSVTNVYILNLALADELFMLGLPFLAAQNALSYWPFGSLMCRLVMAVDGINQFTSIFCLTVMSVDRYLAVVHPTRSARWRTAPVARTVSAAVWVASAVVVLPVVVFSGVPRGMSTCHMQWPEPAAAWRAGFIIYTAALGFFGPLLVICLCYLLIVVKVRSAGRRVWAPSCQRRRRSERRVTRMVVAVVALFVLCWMPFYVLNIVNVVCPLPEEPAFFGLYFLVVALPYANSCANPILYGFLSYRFKQGFRRVLLRPSRRVRSQEPTVGPPEKTEEEDEEEEDGEESREGGKGKEMNGRVSQITQPGTSGQERPPSRVASKEQQLLPQEASTGEKSSTMRISYL
  
Inhibitor
Name:
BDBM50369422
Synonyms:
CHEMBL2369738
Type:
Small organic molecule
Emp. Form.:
C76H104N18O19S2
Mol. Mass.:
1637.878
SMILES:
[H][C@@](C)(N)C(=O)NCC(=O)N[C@]1([H])CSSC[C@]([H])(NC(=O)[C@]([H])(CO)NC(=O)[C@]([H])(NC(=O)[C@]([H])(Cc2ccccc2)NC(=O)[C@]([H])(NC(=O)[C@]([H])(CCCCN)NC(=O)[C@@]([H])(Cc2c[nH]c3ccccc23)NC(=O)[C@]([H])(Cc2ccccc2)NC(=O)[C@@]([H])(Cc2ccccc2)NC(=O)[C@]([H])(CC(N)=O)NC(=O)[C@@]([H])(CCCCN)NC1=O)[C@]([H])(C)O)[C@H](C)O)C(O)=O
Structure:
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