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Target
D(1A) dopamine receptor
Ligand
BDBM50094500
Substrate
n/a
Meas. Tech.
ChEMBL_60326 (CHEMBL879567)
Ki
880±n/a nM
Citation
 Hübner, H; Kraxner, J; Gmeiner, P Cyanoindole derivatives as highly selective dopamine D(4) receptor partial agonists: solid-phase synthesis, binding assays, and functional experiments. J Med Chem 43:4563-9 (2000) [PubMed]
Target
Name:
D(1A) dopamine receptor
Synonyms:
D(1A) dopamine receptor | D1AR | DOPAMINE D1 | DRD1 | DRD1_BOVIN | Dopamine receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49330.65
Organism:
BOVINE
Description:
DOPAMINE D1 DRD1 BOVINE::Q95136
Residue:
446
Sequence:
MRTLNTSTMEGTGLVAERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTGPSEGNATSLGKTINNCDSSLSRTYAISSSLISFYIPVAIMIVTYTRIYRIAQKQIRRISALERAAVHAKNCQTTTGNGNPMECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCGSGETKPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPTTNNAIETVSINNNGAVVFSSHHEPRGSISKDCNVVYLIPHAVGSSEGLKKEEAVGIAKPLEKLSPALSVILDYDTDVSLEKIQPITQNGQHPT
  
Inhibitor
Name:
BDBM50094500
Synonyms:
2-[4-(3,4-Dichloro-phenyl)-piperazin-1-ylmethyl]-1H-indole-6-carbonitrile | CHEMBL344602
Type:
Small organic molecule
Emp. Form.:
C20H18Cl2N4
Mol. Mass.:
385.29
SMILES:
Clc1ccc(cc1Cl)N1CCN(Cc2cc3ccc(cc3[nH]2)C#N)CC1
Structure:
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