Reaction Details  Report a problem with these data
Target
Somatostatin receptor type 3
Ligand
BDBM50369894
Substrate
n/a
Meas. Tech.
ChEMBL_200827 (CHEMBL807040)
Ki
84±n/a nM
Citation
 Poitout, L; Roubert, P; Contour-Galcéra, MO; Moinet, C; Lannoy, J; Pommier, J; Plas, P; Bigg, D; Thurieau, C Identification of potent non-peptide somatostatin antagonists with sst(3) selectivity. J Med Chem 44:2990-3000 (2001) [PubMed]
Target
Name:
Somatostatin receptor type 3
Synonyms:
SOMATOSTATIN SST3 | SS-3-R | SS3-R | SS3R | SSR-28 | SSR3_HUMAN | SSTR3 | Somatostatin receptor type 3 (SSTR3)
Type:
Protein
Mol. Mass.:
45855.97
Organism:
Homo sapiens (Human)
Description:
P32745
Residue:
418
Sequence:
MDMLHPSSVSTTSEPENASSAWPPDATLGNVSAGPSPAGLAVSGVLIPLVYLVVCVVGLLGNSLVIYVVLRHTASPSVTNVYILNLALADELFMLGLPFLAAQNALSYWPFGSLMCRLVMAVDGINQFTSIFCLTVMSVDRYLAVVHPTRSARWRTAPVARTVSAAVWVASAVVVLPVVVFSGVPRGMSTCHMQWPEPAAAWRAGFIIYTAALGFFGPLLVICLCYLLIVVKVRSAGRRVWAPSCQRRRRSERRVTRMVVAVVALFVLCWMPFYVLNIVNVVCPLPEEPAFFGLYFLVVALPYANSCANPILYGFLSYRFKQGFRRVLLRPSRRVRSQEPTVGPPEKTEEEDEEEEDGEESREGGKGKEMNGRVSQITQPGTSGQERPPSRVASKEQQLLPQEASTGEKSSTMRISYL
  
Inhibitor
Name:
BDBM50369894
Synonyms:
CHEMBL1202953
Type:
Small organic molecule
Emp. Form.:
C29H30N4
Mol. Mass.:
434.5753
SMILES:
C1C2CC3CC1CC(C2)C31NC(Cc2c1[nH]c1ccccc21)c1nc(c[nH]1)-c1ccccc1 |TLB:4:3:0.5.6:8,10:9:2:0.4.5,14:9:2:0.4.5,14:9:0.5.6:8,THB:4:5:8:2.3.9,6:5:2:7.8.9,6:7:2:0.4.5,9:3:0:6.7.8,9:7:0:2.3.4,10:9:0.5.6:8,(1.33,-.77,;1.33,.77,;,1.54,;-1.33,.77,;-1.33,-.77,;,-1.54,;1.33,-.77,;1.33,.77,;1.73,1.42,;,1.54,;.72,2.96,;-.05,4.29,;-1.59,4.29,;-2.36,2.96,;-1.59,1.62,;-2.62,.48,;-4.02,1.1,;-5.43,.48,;-6.67,1.38,;-6.51,2.91,;-5.11,3.54,;-3.86,2.63,;.72,5.62,;2.24,5.77,;2.56,7.27,;1.23,8.04,;.08,7.01,;3.97,7.9,;5.27,7.1,;6.63,7.83,;6.67,9.37,;5.36,10.18,;4.01,9.44,)|
Structure:
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