Reaction Details  Report a problem with these data
Target
Adenosine receptor A3
Ligand
BDBM50090850
Substrate
n/a
Meas. Tech.
ChEMBL_31710 (CHEMBL873053)
Ki
425±n/a nM
Citation
 Jacobson, KA; Gao, ZG; Chen, A; Barak, D; Kim, SA; Lee, K; Link, A; Rompaey, PV; van Calenbergh, S; Liang, BT Neoceptor concept based on molecular complementarity in GPCRs: a mutant adenosine A(3) receptor with selectively enhanced affinity for amine-modified nucleosides. J Med Chem 44:4125-36 (2001) [PubMed]
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Homo sapiens (Human)
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
  
Inhibitor
Name:
BDBM50090850
Synonyms:
(2R,3S,4R,5R)-2-Aminomethyl-5-(6-amino-purin-9-yl)-tetrahydro-furan-3,4-diol | 2-Aminomethyl-5-(6-amino-purin-9-yl)-tetrahydro-furan-3,4-diol | 5'-amino-5'-deoxyadenosine | CHEMBL302376
Type:
Small organic molecule
Emp. Form.:
C10H14N6O3
Mol. Mass.:
266.2566
SMILES:
NC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12
Structure:
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