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Target
Mu-type opioid receptor
Ligand
BDBM50027094
Substrate
n/a
Meas. Tech.
ChEMBL_148230 (CHEMBL753390)
Ki
37±n/a nM
Citation
 Black, SL; Chauvignac, C; Grundt, P; Miller, CN; Wood, S; Traynor, JR; Lewis, JW; Husbands, SM Guanidino N-substituted and N,N-disubstituted derivatives of the kappa-opioid antagonist GNTI. J Med Chem 46:5505-11 (2003) [PubMed]  Article
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44789.51
Organism:
Homo sapiens (Human)
Description:
P35372
Residue:
400
Sequence:
MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM50027094
Synonyms:
CHEMBL2112374
Type:
Small organic molecule
Emp. Form.:
C28H31N5O3
Mol. Mass.:
485.5774
SMILES:
[H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@@]5(O)Cc1c2[nH]c2ccc(CNC(N)=N)cc12)ccc3O |THB:10:9:17:4.5.6|
Structure:
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