Reaction Details  Report a problem with these data
Target
Cannabinoid receptor 1
Ligand
BDBM50126860
Substrate
n/a
Meas. Tech.
ChEMBL_46642 (CHEMBL658898)
Ki
>1000±n/a nM
Citation
 López-Rodríguez, ML; Viso, A; Ortega-Gutiérrez, S; Fowler, CJ; Tiger, G; de Lago, E; Fernández-Ruiz, J; Ramos, JA Design, synthesis, and biological evaluation of new inhibitors of the endocannabinoid uptake: comparison with effects on fatty acid amidohydrolase. J Med Chem 46:1512-22 (2003) [PubMed]  Article
Target
Name:
Cannabinoid receptor 1
Synonyms:
Brain-type cannabinoid receptor | CANNABINOID CB1 | CB-R | CB1 | CNR1_RAT | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cnr1 | Skr6
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
52856.55
Organism:
Rattus norvegicus (rat)
Description:
P20272
Residue:
473
Sequence:
MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQEKMTAGDNSPLVPAGDTTNITEFYNKSLSSFKENEENIQCGENFMDMECFMILNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFVDFHVFHRKDSPNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCKKLQSVCSDIFPLIDETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQPLDNSMGDSDCLHKHANNTASMHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
  
Inhibitor
Name:
BDBM50126860
Synonyms:
CHEMBL38282 | Icosa-5,8,11,14-tetraenoic acid (1-methyl-2-thiophen-3-yl-ethyl)-amide
Type:
Small organic molecule
Emp. Form.:
C27H41NOS
Mol. Mass.:
427.686
SMILES:
CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)NC(C)Cc1ccsc1
Structure:
Search PDB for entries with ligand similarity: